Best Strategies for Maintaining Long-Term Weight Loss

Do you wonder why, after losing weight last year, you’re back to where you started? Are you telling yourself that this time, you will strengthen your resolve and make it stick? A surprising new Australian study helps explain that your lack of willpower may not be to blame.

best strategies for weight loss

Published recently in the New England Journal of Medicine, the study documented results for 34 overweight and obese volunteers. They consumed a very restrictive diet of 500-550 calories a day and after 10 weeks lost about 30 pounds, or 14% of their initial body weight. Over the next year, participants regained some weight but were still about 17 pounds, or 8% below their starting weights by the end of the study.

Surprisingly though, participants’ blood tests showed that there were many hormones responsible for weight gain that were still not back to their starting levels, even a year after weight loss. For example, leptin, which is produced by fat cells and sends satiety signals to the brain, dipped by 65% during the weight loss period but was still found to be about 35% lower than at the start of the study. Ghrelin, a gastrointestinal hormone that drives hunger, was similarly disrupted: it rose notably during the weight loss period but still remained significantly higher than at the beginning of the study.

Beyond hunger hormones driving appetite, obesity expert Donna Ryan, MD advises that there is an additional factor causing weight-losers to pack the pounds back on. She says, “Your appetite is increased and your metabolic rate is decreased, both of which promote energy storage. That’s the double whammy that’s trying to get you to gain the weight back. It’s what we call metabolic adaptation.” Dr. Ryan is Associate Executive Director for Clinical Research for the Nutrition Obesity Research Center, Pennington Biomedical Research Center in Baton Rouge, Louisiana.

So, if there are multiple biological mechanisms that must be overcome to maintain weight loss, even after a year, what are the best strategies for success? Here’s what works:

Physical activity is the single most important factor to counteract the metabolic handicap. The National Weight Control Registry (NWCR) tracks the behaviors of more than 10,000 people who have been successful at maintaining long-term weight loss.  Almost all of them, 90% in fact, exercise on average for about an hour a day and the most frequently reported activity is walking.

Fight increased appetite by filling up on fruits and vegetables. Dr. Ryan recommends eating a healthy, balanced diet with an emphasis on low-density, high nutrition fruits and vegetables to help trigger satiety at a lower caloric intake.

Adopt and maintain a different lifestyle for good. “The metabolic adaptation to weight loss is something that never goes away,” says Dr. Ryan. A person who loses weight has a caloric handicap compared to another person who was always stable at that same weight. For example, a person who weighed 230 pounds and lost 30 pounds cannot eat as many calories as the person who always weighed 200 pounds, if she wants to maintain the weight loss. The greater the weight loss, the greater the caloric handicap will be.

Never skip breakfast. In the NWCR, 78% of successful weight-loss maintainers eat breakfast every day.

Weigh yourself daily to stay on track. This allows you to modify your diet and exercise habits as soon as your weight starts to creep upwards.

Keep a food diary. Recording what you eat can double your weight loss, according to a study from Kaiser Permanente’s Center for Health Research. But it is also an effective strategy for shedding pounds that have crept back on. Dr. Ryan puts her relapsing patients back on “the little blue book” food diary to get them back on track.


GE and MedHelp created the free iPhone app, My Diet Diary-Calorie Counter, a high-tech way for users track their caloric intake, exercise and chart their progress to achieve weight loss goals. Read our other posts: “The Anti-Diet: Winning the War on Obesity” and “How to Kick the Added Sugar Habit.” 

Originally published on GE Healthy Outlook, April 3, 2012. Copyright Jane Langille.

, , , , , , , , , , , ,

5 Responses to Best Strategies for Maintaining Long-Term Weight Loss

  1. It Works Body Wraps That Work July 19, 2012 at 9:08 pm #

    First off I would like to say excellent blog! I had a quick
    question which I’d like to ask if you don’t mind. I was interested to know how you center yourself and clear your head before writing. I have had a hard time clearing my thoughts in getting my thoughts out. I do enjoy writing however it just seems like the first 10 to 15 minutes are wasted simply just trying to figure out how to begin. Any suggestions or tips? Many thanks!

    • Jane July 22, 2012 at 6:33 pm #

      Try turning off your email and just write for those first 10 to 15 minutes without expecting it to be perfect. I will often try one starting point only to scrap it later and revise. Another trick is to use a mind mapping app like MindNode (Mac app store) where you can plan the flow ahead of time in point form with thought branches, before you start actually writing.


  1. My Pick: Fitbit Flex Fitness Band - April 16, 2017

    […] At a recent conference for the Professional Writers Association of Canada, another writer friend was wearing a Fitbit Flex that she had ordered online via in March. She showed me her progress on the online dashboard and she’s making significant positive changes to her health. The software integrates with MyFitnessPal, a terrific app for tracking diet and nutrition information. We walked for an hour one morning and her Flex measured that as 7,800 steps, a significant portion of the magical 10,000 steps per day that has been shown to help maintain long-term weight loss. […]

  2. The Anti-Diet: Winning the War on Obesity - November 2, 2016

    […] amount of weight and kept it off for a long period of time. Check out our earlier posts, “Best Strategies for Maintaining Long Term Weight Loss,” and “How to Kick the Added Sugar […]

  3. Successful Long-Term Weight Loss Strategies - Jane Langille - February 3, 2015

    […] wrote about the National Weight Control Registry (NWCR) almost three years ago, in the story, Best Strategies for Maintaining Long-Term Weight Loss. Last March 2014, I met James O. Hill at a presentation for health journalists at the Anschutz […]